57268-33-4: Dantrolene Related Compound B

Dantrolene Related Compound B (CAS No.: 57268-33-4) or 5-(4-Nitrophenyl)-2-furaldehyde-2-carboxymethyl semicarbazone is a Dantrolene-related impurity. Dantrolene sodium is known to alter some steps in the excitation-contraction coupling system. Dantrolene can both increase the rheobase potential and raises the steepness of the strength-duration curve for the mechanical threshold.

Additional information

Additional information

Catalogue No.

VE006882

CAS No.

57268-33-4

Molecular Formula

C14H12N4O6

Molecular Weight

332.27

IUPAC Name

5-(4-Nitrophenyl)-2-furaldehyde-2-carboxymethyl semicarbazone

References

"Tawakkul, Mobin A., et al. “Development and Application of a Validated Stability-Indicating Ultra-Performance Liquid Chromatography (UPLC) Method for the Determination of Dantrolene and Its Related Impurities.” Clinical Research and Regulatory Affairs, vol. 27, no. 1, Feb. 2010, pp. 21–29, https://doi.org/10.3109/10601331003623309.?Morgan, K. G., and S. H. Bryant. “The Mechanism of Action of Dantrolene Sodium.” Journal of Pharmacology and Experimental Therapeutics, vol. 201, no. 1, American Soci

Status

In-stock

Cookie	Duration	Description
cookielawinfo-checkbox-advertisement	1 year	Set by the GDPR Cookie Consent plugin, this cookie is used to record the user consent for the cookies in the "Advertisement" category .
cookielawinfo-checkbox-analytics	11 months	This cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Analytics".
cookielawinfo-checkbox-functional	11 months	The cookie is set by GDPR cookie consent to record the user consent for the cookies in the category "Functional".
cookielawinfo-checkbox-necessary	11 months	This cookie is set by GDPR Cookie Consent plugin. The cookies is used to store the user consent for the cookies in the category "Necessary".
cookielawinfo-checkbox-others	11 months	This cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Other.
cookielawinfo-checkbox-performance	11 months	This cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Performance".
CookieLawInfoConsent	1 year	Records the default button state of the corresponding category & the status of CCPA. It works only in coordination with the primary cookie.
viewed_cookie_policy	11 months	The cookie is set by the GDPR Cookie Consent plugin and is used to store whether or not user has consented to the use of cookies. It does not store any personal data.

Cookie	Duration	Description
bcookie	1 year	LinkedIn sets this cookie from LinkedIn share buttons and ad tags to recognize browser ID.
bscookie	1 year	LinkedIn sets this cookie to store performed actions on the website.
lang	session	LinkedIn sets this cookie to remember a user's language setting.
lidc	1 day	LinkedIn sets the lidc cookie to facilitate data center selection.
UserMatchHistory	1 month	LinkedIn sets this cookie for LinkedIn Ads ID syncing.

Cookie	Duration	Description
_ga	2 years	The _ga cookie, installed by Google Analytics, calculates visitor, session and campaign data and also keeps track of site usage for the site's analytics report. The cookie stores information anonymously and assigns a randomly generated number to recognize unique visitors.
_ga_QDGR88LYST	2 years	This cookie is installed by Google Analytics.
_gat_UA-152546504-1	1 minute	A variation of the _gat cookie set by Google Analytics and Google Tag Manager to allow website owners to track visitor behaviour and measure site performance. The pattern element in the name contains the unique identity number of the account or website it relates to.
_gid	1 day	Installed by Google Analytics, _gid cookie stores information on how visitors use a website, while also creating an analytics report of the website's performance. Some of the data that are collected include the number of visitors, their source, and the pages they visit anonymously.

Cookie	Duration	Description
AnalyticsSyncHistory	1 month	No description
li_gc	5 months 27 days	No description

57268-33-4: Dantrolene Related Compound B

Additional information

Other products related to dantrolene impurities