57268-33-4: Dantrolene Related Compound B

Dantrolene Related Compound B (CAS No.: 57268-33-4) or 5-(4-Nitrophenyl)-2-furaldehyde-2-carboxymethyl semicarbazone is a Dantrolene-related impurity. Dantrolene sodium is known to alter some steps in the excitation-contraction coupling system. Dantrolene can both increase the rheobase potential and raises the steepness of the strength-duration curve for the mechanical threshold.

Additional information

Catalogue No.

VE006882

CAS No.

57268-33-4

Molecular Formula

C14H12N4O6

Molecular Weight

332.27

IUPAC Name

5-(4-Nitrophenyl)-2-furaldehyde-2-carboxymethyl semicarbazone

References

"Tawakkul, Mobin A., et al. “Development and Application of a Validated Stability-Indicating Ultra-Performance Liquid Chromatography (UPLC) Method for the Determination of Dantrolene and Its Related Impurities.” Clinical Research and Regulatory Affairs, vol. 27, no. 1, Feb. 2010, pp. 21–29, https://doi.org/10.3109/10601331003623309.?Morgan, K. G., and S. H. Bryant. “The Mechanism of Action of Dantrolene Sodium.” Journal of Pharmacology and Experimental Therapeutics, vol. 201, no. 1, American Soci

Status

In-stock