1188271-71-7: Dexamethasone Impurity 4

1188271-71-7: Dexamethasone Impurity 4

Also known as 21-Dehydro Desoxymetasone, it is a 21-dihydro derivative of Dexamethasone which is a drug of choice in patients affected by the COVID-19 virus and was recommended for patients receiving respiratory support.

Additional information on CAS 1188271-71-7

Catalogue No.

VE005952
CAS No.

1188271-71-7
Molecular Formula

C22H27FO4
Molecular Weight

374.4
Parent drug

Dexamethasone
IUPAC Name

2-((8S, 9R, 10S, 11S, 13S, 14S, 16R, 17S)-9-fluoro-11-hydroxy10, 13, 16-trimethyl-3-oxo-6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17-dodecahydro-3Hcyclopenta[a]phenanthren-17-yl)-2-oxoacetaldehyde
Synonyms

21-Dehydro Desoxymetasone
References

Martin, Kumiko O., and Carl Monder. “Oxidation of Steroids with the 20v-Hydroxy-21-Oxo Side Chain to 20v-Hydroxy-21-Oic Acids by Horse Liver Aldehyde Dehydrogenases.” Journal of Steroid Biochemistry, vol. 9, no. 12, Dec. 1978, pp. 1233–40, https://doi.org/10.1016/0022-4731(78)90018-3.?Lester, Mohammed, et al. “The Use of Dexamethasone in the Treatment of COVID-19.” Annals of Medicine and Surgery, vol. 56, Aug. 2020, pp. 218–19, https://doi.org/10.1016/j.amsu.2020.07.004.?
Status

In-stock

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1188271-71-7: Dexamethasone Impurity 4

1188271-71-7: Dexamethasone Impurity 4
Catalogue No.

VE005952
CAS No.

1188271-71-7
Molecular Formula

C22H27FO4
Molecular Weight

374.4
Parent drug

Dexamethasone
IUPAC Name

2-((8S, 9R, 10S, 11S, 13S, 14S, 16R, 17S)-9-fluoro-11-hydroxy10, 13, 16-trimethyl-3-oxo-6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17-dodecahydro-3Hcyclopenta[a]phenanthren-17-yl)-2-oxoacetaldehyde
Synonyms

21-Dehydro Desoxymetasone
References

Martin, Kumiko O., and Carl Monder. “Oxidation of Steroids with the 20v-Hydroxy-21-Oxo Side Chain to 20v-Hydroxy-21-Oic Acids by Horse Liver Aldehyde Dehydrogenases.” Journal of Steroid Biochemistry, vol. 9, no. 12, Dec. 1978, pp. 1233–40, https://doi.org/10.1016/0022-4731(78)90018-3.?Lester, Mohammed, et al. “The Use of Dexamethasone in the Treatment of COVID-19.” Annals of Medicine and Surgery, vol. 56, Aug. 2020, pp. 218–19, https://doi.org/10.1016/j.amsu.2020.07.004.?
Status

In-stock
ListName

Dexamethasone Impurity 4
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