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Includes: HPLC, MASS/LC-MS, 1H NMR, FT-IR, Potency, Structure Elucidation Report (SER), and additional analytical data depending on the product.

987-24-6Dexamethasone Acetate EP Impurity D

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Catalogue No.:	VL273022
CAS No.:	987-24-6
Mol. Formula:	C24H31FO6
Mol. Weight:	434.5 g/mol

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Additional information on CAS 987-24-6

Parent drug

Dexamethasone

IUPAC Name

9-fluoro-11β, 17-dihydroxy-16β-methyl-3, 20-dioxopregna-1, 4-dien-21-yl acetate

Synonyms

Betamethasone 21-Acetate; (11?, 16?)-21-(Acetyloxy)-9-fluoro-11, 17-dihydroxy-16-methylpregna-1, 4-diene-3, 20-dione; 9-Fluoro-11?, 17, 21-trihydroxy-16?-methylpregna-1, 4-diene-3, 20-dione 21-acetate; Betamethasone Acetate;

Smiles

CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)COC(=O)C)O)C)O)F)C

Characterization Data (Included)

HPLC, MASS/LC-MS, 1H NMR, FT-IR, Potency, and Structure Elucidation Report (SER).

Additional Characterization Data

QNMR, D2O Exchange, 13C NMR, 13C APT, COSY NMR, NOESY NMR, 15N NMR, HSQC NMR, HMQC NMR, and HMBC NMR. These are available upon request and may be free or subject to additional charges.

Description

Also known as Betamethasone 21-Acetate. It is an impurity of Dexamethasone which is an influential synthetic corticosteroid having antiinflammatory and immunosuppressive properties widely used as an anti-inflammatory agent.

References

Chen, Quan, et al. “A Validated, Stability-Indicating HPLC Method for the Determination of Dexamethasone Related Substances on Dexamethasone-Coated Drug-Eluting Stents.” Journal of Pharmaceutical and Biomedical Analysis, vol. 48, no. 3, Nov. 2008, pp. 732–38, https://doi.org/10.1016/j.jpba.2008.07.010.