Elagolix Nitroso Impurity
Elagolix Nitroso Impurity or (R)-4-((2-(5-(2-Fluoro-3-methoxyphenyl)-3-(2-fluoro-6-(trifluoromethyl)benzyl)-4-methyl-2,6-dioxo-3,6-dihydropyridine-1(2H)-yl)-1-phenylethyl)(nitroso)amino)butanoic acid,is a gonadotropin-releasing hormone receptor antagonist, nonpeptide that used to treat moderate to severe pain in endometriosis. it acts to binding competitively to GnRH receptors in the pituitary gland.
Additional information on Elagolix Nitroso Impurity
VE009406
N/A
C32H29F5N4O6
660.6 g/mol
Elagolix
(R)-4-((2-(5-(2-Fluoro-3-methoxyphenyl)-3-(2-fluoro-6-(trifluoromethyl)benzyl)-4-methyl-2, 6-dioxo-3, 6-dihydropyrimidin-1(2H)-yl)-1-phenylethyl)(nitroso)amino)butanoic acid
Entecavir 4-Epimer/ (1S, 3R, 4R)-Entecavir
Shebley, Mohamad, et al. “Clinical Pharmacology of Elagolix: An Oral Gonadotropin-Releasing Hormone Receptor Antagonist for Endometriosis.” Clinical Pharmacokinetics, vol. 59, no. 3, Nov. 2019, pp. 297–309, https://doi.org/10.1007/s40262-019-00840-7.
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