Elagolix Nitroso Impurity

Elagolix Nitroso Impurity or (R)-4-((2-(5-(2-Fluoro-3-methoxyphenyl)-3-(2-fluoro-6-(trifluoromethyl)benzyl)-4-methyl-2,6-dioxo-3,6-dihydropyridine-1(2H)-yl)-1-phenylethyl)(nitroso)amino)butanoic acid,is a gonadotropin-releasing hormone receptor antagonist, nonpeptide that used to treat moderate to severe pain in endometriosis. it acts to binding competitively to GnRH receptors in the pituitary gland.

Additional information

Catalogue No.

VE009406

CAS No.

N/A

Molecular Formula

C32H29F5N4O6

Molecular Weight

660.6 g/mol

IUPAC Name

(R)-4-((2-(5-(2-Fluoro-3-methoxyphenyl)-3-(2-fluoro-6-(trifluoromethyl)benzyl)-4-methyl-2, 6-dioxo-3, 6-dihydropyrimidin-1(2H)-yl)-1-phenylethyl)(nitroso)amino)butanoic acid

Synonyms

Entecavir 4-Epimer/ (1S, 3R, 4R)-Entecavir

References

Shebley, Mohamad, et al. “Clinical Pharmacology of Elagolix: An Oral Gonadotropin-Releasing Hormone Receptor Antagonist for Endometriosis.” Clinical Pharmacokinetics, vol. 59, no. 3, Nov. 2019, pp. 297–309, https://doi.org/10.1007/s40262-019-00840-7. ‌

Status

In-stock