1839619-50-9: Enzalutamide Impurity 7

Enzalutamide Impurity 7 (CAS No.1839619-50-9) or 1,3-bis(4-cyano-3-(trifluoromethyl)phenyl)thiourea. Enzalutamide is a nonsteroidal antiandrogen that binds to the ligand-binding domain and has more affinity. It is used in the treatment of castration-resistant prostate cancer.

Additional information

Catalogue No.

VE006573

CAS No.

1839619-50-9

Molecular Formula

C17H8F6N4S

Molecular Weight

414.33

IUPAC Name

1, 3-bis(4-cyano-3-(trifluoromethyl)phenyl)thiourea

References

"Graff, Julie N., et al. “Early Evidence of Anti-PD-1 Activity in Enzalutamide-Resistant Prostate Cancer.” Oncotarget, vol. 7, no. 33, July 2016, pp. 52810–17, https://doi.org/10.18632/oncotarget.10547. ?Schrader, Andres Jan, et al. “Enzalutamide in Castration-Resistant Prostate Cancer Patients Progressing after Docetaxel and Abiraterone.” European Urology, vol. 65, no. 1, Jan. 2014, pp. 30–36, https://doi.org/10.1016/j.eururo.2013.06.042. ?"

Status

In-stock