Enzalutamide Inhouse Impurity O

Enzalutamide Inhouse Impurity O  a nonsteroidal antiandrogen that binds to the ligand-binding domain and has more affinity. It is used in the treatment of castration-resistant prostate cancer.

Additional information

Catalogue No.

VE008225

CAS No.

N/A

Molecular Formula

C21H18F4N4O3

Molecular Weight

450.39 g/mol

IUPAC Name

4-(N-(1-((4-cyano-3-(trifluoromethyl)phenyl)amino)-2-methyl-1-oxopropan-2-yl)formamido)-2-fluoro-N-methylbenzamide

References

'Graff, Julie N., et al. “Early Evidence of Anti-PD-1 Activity in Enzalutamide-Resistant Prostate Cancer.” Oncotarget, vol. 7, no. 33, July 2016, pp. 52810–17, https://doi.org/10.18632/oncotarget.10547. ?Schrader, Andres Jan, et al. “Enzalutamide in Castration-Resistant Prostate Cancer Patients Progressing after Docetaxel and Abiraterone.” European Urology, vol. 65, no. 1, Jan. 2014, pp. 30–36, https://doi.org/10.1016/j.eururo.2013.06.042 '

Status

In-stock