209253-80-5: Eplerenone 6β-Hydroxy Impurity
Eplerenone 6v-Hydroxy Impurity (CAS No.209253-80-5) or methyl (4aS,4bR,5aR,6aS,7R,9aS,9bR,10S,11R)-11-hydroxy-4a,6a-dimethyl-2,5-dioxo-2,4,4a,4,5a,5,6,6a,8,9,9a,9b,10,11-tetradecahydro-3H,3H-spiro[cyclopenta[1,2]phenanthro[4,4a-b]oxirene-7,2-furan]-10-carboxylate. Eplerenone is a steroid nucleus-based anti-mineralocorticoid that is a competitive and selective aldosterone blocker.
Additional information on CAS 209253-80-5
VE008196
209253-80-5
C24H30O7
430.50 g/mol
Eplerenone
methyl (4aS, 4bR, 5aR, 6aS, 7R, 9aS, 9bR, 10S, 11R)-11-hydroxy-4a, 6a-dimethyl-2, 5-dioxo-2, 4, 4a, 4, 5a, 5, 6, 6a, 8, 9, 9a, 9b, 10, 11-tetradecahydro-3H, 3H-spiro[cyclopenta[1, 2]phenanthro[4, 4a-b]oxirene-7, 2-furan]-10-carboxylate
N/A
"Williams, Gordon H., et al. “Efficacy of Eplerenone versus Enalapril as Monotherapy in Systemic Hypertension.” The American Journal of Cardiology, vol. 93, no. 8, Apr. 2004, pp. 990–96, https://doi.org/10.1016/j.amjcard.2004.01.007. ?"
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