209253-67-8: Eplerenone EP Impurity A
Eplerenone EP Impurity A (CAS No: 209253-67-8) with IUPAC Name 3-Oxo-17a-pregn-4-ene-7a,9:21,17-dicarbolactone is an impurity of Eplerenone. Eplerenone is an aldosterone receptor antagonist and potassium-sparing diuretic used in the therapy of hypertension. Eplerenone therapy has been associated with transient elevations in serum aminotransferase levels but has yet to be linked to cases of clinically apparent drug-induced liver disease.
Additional information on CAS 209253-67-8
3-Oxo-17α-pregn-4-ene-7α, 9:21, 17-dicarbolactone
“Eplerenone.” Nih.gov, National Institute of Diabetes and Digestive and Kidney Diseases, 13 Oct. 2021, http://www.ncbi.nlm.nih.gov/books/NBK547930/.
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