Fluvastatin EP Impurity E

Status: In-stock

It is an impurity present in Fluvastatin, Fluvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A reductase, HMG-CoA reductase is responsible for converting HMG-CoA to mevalonate, Inhibition results in a decrease in hepatic cholesterol levels which stimulates the synthesis of LDL receptors and increases hepatic uptake of LDL cholesterol, the result is decreased levels of plasma total and LDL cholesterol. which is used to lower lipid levels and reduce the risk of cardiovascular disease.

Additional information on Fluvastatin EP Impurity E

Catalogue No. VE009840
CAS No. N/A
Molecular Formula C24H22FNO3
Molecular Weight 391.4 g/mol
Parent drug Fluvastatin
IUPAC Name (6R)-6-[(E)-2-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]ethenyl]-4-hydroxy-5, 6-dihydro-2H-pyran-2-one
Synonyms N/A
References Adams, S. P., Sekhon, S. S., Tsang, M., & Wright, J. M. (2018). Fluvastatin for lowering lipids. Cochrane Database of Systematic Reviews, 2018(3). https://doi.org/10.1002/14651858.cd012282.pub2
Status In-stock

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