122111-05-1: Gemcitabine EP Impurity B (HCl Salt)

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Gemcitabine EP Impurity B (HCl Salt)(CAS No. 122111-05-1) is an impurity present in Gemcitabine, Gemcitabine is a nucleoside analog that mediates its antitumor effects by promoting apoptosis of malignant cells undergoing DNA synthesis, gemcitabine inhibited the growth of human xenografts from carcinoma of the lung, pancreas, ovaries, head, and neck, and breast, which demonstrated cytotoxic effect

Additional information on CAS 122111-05-1

Catalogue No. VE008524
CAS No. 122111-05-1
Molecular Formula C9H11F2N3O4 • HCl
Molecular Weight 299.66 g/mol
Parent drug Gemcitabine
IUPAC Name 4-amino-1-((2S, 4R, 5R)-3, 3-difluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one hydrochloride
Synonyms Gemcitabine alpha-Isomer ( HCl Salt )
References "Ciccolini, J., Serdjebi, C., Peters, G. J., & Giovannetti, E. (2016). Pharmacokinetics and pharmacogenetics of Gemcitabine as a mainstay in adult and pediatric oncology: an EORTC-PAMM perspective. Cancer Chemotherapy and Pharmacology, 78(1), 1–12. https://doi.org/10.1007/s00280-016-3003-0 ‌"
Status In-stock

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122111-05-1: Gemcitabine EP Impurity B (HCl Salt)

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