252186-78-0: Lamotrigine EP Impurity A
Lamotrigine EP Impurity A (CAS No: 252186-78-0) or Lamotrigine Related Compound C / Oxo Impurity is an impurity of Lamotrigine that is broadly used antiepileptic used for the treatment of partial seizures, primary and secondary tonic-clonic seizures, and seizures related to Lennox-Gastaut syndrome.
Additional information on CAS 252186-78-0
VL980002
252186-78-0
C₉H₆Cl₂N₄O
257.08
Lamotrigine
3-Amino-6-(2, 3-dichlorophenyl)-1, 2, 4-tryriazin-5(2H)-one; 3-Amino-6-(2, 3-dichlorophenyl)-1, 2, 4-tryriazin-5(4H)-one
Lamotrigine Related Compound C; Oxo Impurity; 3-Amino-6-(2, 3-dichlorophenyl)-1, 2, 4-tryriazin-5(2H)-one; 3-Amino-6-(2, 3-dichlorophenyl)-1, 2, 4-tryriazin-5(4H)-one; USP Lamotrigine Related Compound C; Lamotrigine Imp. A (EP); Lamotrigine EP Impurity A; Lamotrigine USP Related Compound C
C1=CC(=C(C(=C1)Cl)Cl)C2=NN=C(NC2=O)N
?olovi?, Jelena, et al. “Robust Optimization of Chaotropic Chromatography Assay for Lamotrigine and Its Two Impurities in Tablets.” Chromatographia, vol. 82, no. 2, Dec. 2018, pp. 565–77, https://doi.org/10.1007/s10337-018-3661-7.
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