70844-48-3: Methotrexate EP Impurity E

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Methotrexate EP Impurity E (CAS No.70844-48-3) Or 4-[[(2, 4-Diaminopteridin-6-yl)methyl]methyl amino]benzoic acid hemihydrochloride salt, The anti-metabolite methotrexate (MTX) is most frequently used in chemotherapy and as an immunosuppressant in autoimmune disorders. This exercise explains the benefits of methotrexate as a treatment for a wide range of neoplastic disorders, as well as how it works and when it shouldn’t be used. This activity will focus on the mechanism of action, adverse event profile, and other critical elements (uses, dosing, pharmacodynamics, pharmacokinetics, monitoring, and relevant interactions) important for members of the multidisciplinary healthcare team in managing patients with cancer and autoimmune diseases.

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Additional information on CAS 70844-48-3

Catalogue No. VE009027
CAS No. 70844-48-3
Molecular Formula C15H15N7O2.1/2HCl
Molecular Weight 343.56 g/mol
Parent drug Methotrexate
IUPAC Name 4-[[(2, 4-Diaminopteridin-6-yl)methyl]methyl amino]benzoic acid hemihydrochloride salt
Smiles CN(Cc2cnc1nc(N)nc(N)c1n2)c3ccc(C(=O)O)cc3.Cl
Synonyms Methotrexate Related Compound E (Hemihydrochloride salt)
References Hannoodee, Maryam, and Meenal Mittal. “Methotrexate.” Nih.gov, StatPearls Publishing, 20 Jan. 2022, http://www.ncbi.nlm.nih.gov/books/NBK556114/. ‌
Status In-stock

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70844-48-3: Methotrexate EP Impurity E

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