67022-39-3: Methotrexate EP Impurity H

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Methotrexate EP Impurity H(CAS No. 67022-39-3) is an impurity present in Methotrexate, Methotrexate is a folate derivative that inhibits several enzymes responsible for nucleotide synthesis, Methotrexate inhibits enzymes responsible for nucleotide synthesis which prevents cell division and leads to anti-inflammatory actions, which is used to treat inflammation caused by arthritis.

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Additional information on CAS 67022-39-3

Catalogue No. VE008555
CAS No. 67022-39-3
Molecular Formula C21H24N8O5
Molecular Weight 468.47 g/mol
Parent drug Methotrexate
IUPAC Name (2S)-2-[[4-[[(2, 4-Diaminopteridin-6-yl)methyl]methylamino]benzoyl]amino]-5-methoxy-5-oxopentanoic acid
Smiles CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)OC)C(=O)O
Synonyms Methotrexate 5-Methyl Ester / Methotrexate γ-Methyl Ester
References Bedoui, Y., Guillot, X., Sélambarom, J., Guiraud, P., Giry, C., Jaffar-Bandjee, M. C., … Gasque, P. (2019). Methotrexate an Old Drug with New Tricks. International Journal of Molecular Sciences, 20(20), 5023. https://doi.org/10.3390/ijms20205023
Status In-stock

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67022-39-3: Methotrexate EP Impurity H

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