N-Nitroso Olmesartan Medoxomil Impurity

Status: Under Development

It belongs to Nitrosamine impurities which are referred as as Class 1 impurities, and are potentially genotoxic, known mutagenic carcinogens by ICH M7.

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Additional information on N-Nitroso Olmesartan Medoxomil Impurity

Catalogue No. VE007896
Molecular Formula C29H29N7O7
Molecular Weight 587.58 g/mol
Parent drug Olmesartan
IUPAC Name (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 4-(2-hydroxypropan-2-yl)-1-((2'-(1-nitroso-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-propyl-1H-imidazole-5-carboxylate
Synonyms N/A
References Chidella, Kartheek Srinivas, et al. “Ultra-Sensitive LC-MS/MS Method for the Trace Level Quantification of Six Potential Genotoxic Nitrosamine Impurities in Telmisartan.” American Journal of Analytical Chemistry, vol. 12, no. 06, 2021, pp. 227–40, https://doi.org/10.4236/ajac.2021.126014.
Status Under Development

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