126209-21-0: N-Nitroso Pirfenidone EP Impurity A

N-Nitroso Pirfenidone EP Impurity A (CAS No.126209-21-0) Or N-(5-methylpyridin-2-yl)nitrous amide, N-Nitroso Pirfenidone EP Impurity A is an impurity present in Pirfenidone, pirfenidone abrogates TGF-β1-stimulated collagen synthesis by inhibiting the upregulation of HSP47 and Col1 RNA in a concentration-dependent manner, which shows antifibrotic, anti-inflammatory, and antioxidant effects.

Additional information

Catalogue No.

VE009705

CAS No.

126209-21-0

Molecular Formula

C6H7N3O

Molecular Weight

137.1 g/mol

IUPAC Name

N-(5-methylpyridin-2-yl)nitrous amide

Synonyms

5-Methyl-N-nitroso-2-pyridinamine

References

Margaritopoulos, G., Vasarmidi, E., & Antoniou, K. (2016). Pirfenidone in the treatment of idiopathic pulmonary fibrosis: an evidence-based review of its place in therapy. Core Evidence, Volume 11, 11–22. https://doi.org/10.2147/ce.s76549

Status

In-stock