126209-21-0: N-Nitroso Pirfenidone EP Impurity A

126209-21-0: N-Nitroso Pirfenidone EP Impurity A

N-Nitroso Pirfenidone EP Impurity A (CAS No.126209-21-0) Or N-(5-methylpyridin-2-yl)nitrous amide, N-Nitroso Pirfenidone EP Impurity A is an impurity present in Pirfenidone, pirfenidone abrogates TGF-β1-stimulated collagen synthesis by inhibiting the upregulation of HSP47 and Col1 RNA in a concentration-dependent manner, which shows antifibrotic, anti-inflammatory, and antioxidant effects.

Additional information on CAS 126209-21-0

Catalogue No.

VE009705
CAS No.

126209-21-0
Molecular Formula

C6H7N3O
Molecular Weight

137.1 g/mol
Parent drug

Pirfenidone
IUPAC Name

N-(5-methylpyridin-2-yl)nitrous amide
Synonyms

5-Methyl-N-nitroso-2-pyridinamine
References

Margaritopoulos, G., Vasarmidi, E., & Antoniou, K. (2016). Pirfenidone in the treatment of idiopathic pulmonary fibrosis: an evidence-based review of its place in therapy. Core Evidence, Volume 11, 11–22. https://doi.org/10.2147/ce.s76549
Status

In-stock

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126209-21-0: N-Nitroso Pirfenidone EP Impurity A

126209-21-0: N-Nitroso Pirfenidone EP Impurity A
Catalogue No.

VE009705
CAS No.

126209-21-0
Molecular Formula

C6H7N3O
Molecular Weight

137.1 g/mol
Parent drug

Pirfenidone
IUPAC Name

N-(5-methylpyridin-2-yl)nitrous amide
Synonyms

5-Methyl-N-nitroso-2-pyridinamine
References

Margaritopoulos, G., Vasarmidi, E., & Antoniou, K. (2016). Pirfenidone in the treatment of idiopathic pulmonary fibrosis: an evidence-based review of its place in therapy. Core Evidence, Volume 11, 11–22. https://doi.org/10.2147/ce.s76549
Status

In-stock
ListName

N-Nitroso Pirfenidone EP Impurity A
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