Status: Under Development

(1-(2′-(1-Nitroso-1H-tetrazol-5-yl)-[1,1′-biphenyl]-4-yl)-2-oxohexyl)-L-valine is an impurity present in Valsartan, Valsartan belongs to the angiotensin II receptor blocker, ARBs selectively bind to angiotensin receptor 1 (AT1) and prevent the protein angiotensin II from binding and exerting its hypertensive effect, or in combination with other antihypertensive agents and to manage heart failure in patients who are intolerant to ACE inhibitors.

Additional information on (1-(2'-(1-Nitroso-1H-tetrazol-5-yl)-[1 | 1'-biphenyl]-4-yl)-2-oxohexyl)-L-valine

Catalogue No. VE009745
Molecular Formula C24H28N6O4
Molecular Weight 464.5 g/mol
Parent drug Valsartan
IUPAC Name (1-(2'-(1-Nitroso-1H-tetrazol-5-yl)-[1, 1'-biphenyl]-4-yl)-2-oxohexyl)-L-valine
Synonyms N/A
Smiles CCCCC(=O)C(NC(C(=O)O)C(C)C)c3ccc(c1ccccc1c2nnnn2N=O)cc3
References "Abraham, I. (2011). Real-world effectiveness of valsartan on hypertension and total cardiovascular risk: review and implications of a translational research program. Vascular Health and Risk Management, 209. https://doi.org/10.2147/vhrm.s9434 "
Status Under Development

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