2835-77-0: Nepafenac Impurity A
Also known as 2-Aminobenzophenone, it is an impurity present in Nepafenac that is an NSAID which shows that preoperative treatment using nonsteroidal anti-inflammatory drugs has shown to be efficient in maintaining mydriasis throughout cataract surgery with the mechanism of their action is dependent on their ability to cause cyclooxygenase inhibition.
Additional information on CAS 2835-77-0
2-Aminobenzophenone; 2-Aminophenyl Phenyl Ketone; (2-Aminophenyl)phenylmethanone; (2-Aminophenyl)phenylmethanone; 2-(Phenylcarbonyl)aniline; 2-Aminobenzophenone; 2-Aminophenyl Phenyl Ketone; 2-Benzoylaniline; 2-Benzoylbenzenamine; NSC 9422; o-Aminobenzophenone; o-Aminophenyl Phenyl Ketone; o-Benzoylaniline
Lipiec-Abramska, El?bieta, et al. “Development and Validation of High Performance Liquid Chromatography with a Spectrophotometric Detection Method for the Chemical Purity and Assay of Nepafenac.” Journal of Pharmaceutical and Biomedical Analysis, vol. 91, Mar. 2014, pp. 1–6, https://doi.org/10.1016/j.jpba.2013.12.009.?Lira, Rodrigo PessoaCavalcanti, et al. “Effect of Preoperative Use of Topical Prednisolone Acetate, Ketorolac Tromethamine, Nepafenac and Placebo, on the Maintenance of Intraoperati
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