71791-90-7: Nicardipine Bis Analog (free base)

Nicardipine Bis Analog (free base) (CAS No: 71791-90-7) is an impurity present in nicardipine which is an antagonist of calcium influx through the slow channel of the cell membrane and is an effective and relatively well-tolerated medication for stable effort angina and rests angina due to coronary artery spasm.

Additional information

Catalogue No.

VE007387

CAS No.

71791-90-7

Molecular Formula

C35H40N4O6

Molecular Weight

612.72 g/mol

IUPAC Name

1, 4-Dihydro-2, 6-dimethyl-4-(3-nitrophenyl)-3, 5-Pyridinedicarboxylic acid bis[2-[methyl(phenylmethyl)amino]ethyl] ester

References

“IDENTIFICATION and CHARACTERIZATION of a NOVEL POTENTIAL DEGRADANT and DEVELOPMENT and VALIDATION of STABILITY-INDICATING RP-LC METHOD for NICARDIPINE IMPURITIES in INJECTABLE DOSAGE FORM.” Journal of Liquid Chromatography & Related Technologies, 2013, http://www.tandfonline.com/doi/abs/10.1080/10826076.2012.717056.?Sorkin, Eugene M., and Stephen P. Clissold. “Nicardipine.” Drugs, vol. 33, no. 4, Apr. 1987, pp. 296–345, https://doi.org/10.2165/00003495-198733040-00002.?

Status

In-stock