Rizatriptan EP Impurity D

It is one of impurity present in Rizatriptan, Rizatriptan is a selective agonist of serotonin type 1B and 1D receptors. stimulation of presynaptic 5-HT1D receptors, which serves to inhibit both dural vasodilation and inflammation direct inhibition of trigeminal nuclei cell excitability via 5-HT1B/1D receptor agonism in the brainstem is pharmacological activity at 5-HT2, 5-HT3 or 5-HT4 receptor subtypes or at alpha1 alpha2- beta-adrenergic, dopamine1,dopamine2; muscarinic, benzodiazepine receptors. Rizatriptan also activates 5-HT1 receptors on peripheral terminals of the trigeminal nerve innervating cranial blood vessels, which is used to treat migraines.

Additional information

Catalogue No.

VE0010088

CAS No.

N/A

Molecular Formula

C19H28N5

Molecular Weight

326.46 g/mol

References

Láinez, M. J. (2006). Rizatriptan in the treatment of migraine. Neuropsychiatric Disease and Treatment, 2(3), 247–259. https://doi.org/10.2147/nedt.2006.2.3.247

Status

In-stock