Rizatriptan EP Impurity E

It is one of impurity present in Rizatriptan, Rizatriptan is metabolized by monoamine oxidase A isoenzyme, and Rizatriptan is a selective agonist of serotonin type 1B and 1D receptors. stimulation of presynaptic 5-HT1D receptors, which serves to inhibit both dural vasodilation and inflammation direct inhibition of trigeminal nuclei cell excitability via 5-HT1B/1D receptor agonism in the brainstem is pharmacological activity at 5-HT2, 5-HT3 or 5-HT4 receptor subtypes or at alpha1 alpha2- beta-adrenergic, dopamine1,dopamine2; muscarinic, benzodiazepine receptors. which is used to treat migraines.

Additional information

Catalogue No.

VE0010089

CAS No.

N/A

Molecular Formula

C16H21N5O2S

Molecular Weight

347.44 g/mol

References

Oldman, A., Smith, L. A., McQuay, H. J., Moore, R. A., & Derry, S. (2001). Rizatriptan for acute migraine. Cochrane Database of Systematic Reviews. https://doi.org/10.1002/14651858.cd003221.pub2

Status

In-stock