129212-35-7: Tacrolimus EP Impurity D

Also known as Tacrolimus 8-Epimer, Tacrolimus is a new l-pipecolic acid macrolide lactone, which has shown efficacy in eye inflammatory diseases.

Additional information on CAS 129212-35-7

Catalogue No.

VE006441

CAS No.

129212-35-7

Molecular Formula

C44H69NO12

Molecular Weight

804.02

Parent drug

Tacrolimus

IUPAC Name

(3S, 4R, 5S, 8S, 9E, 12S, 14S, 15R, 16S, 18R, 19R, 26aS)-5, 19-dihydroxy-3-[(1E)-1-[(1R, 3R, 4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-8-(prop-2-en-1-yl)-3, 4, 5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-octadecahydro-7H-15, 19-epoxypyrido[2, 1-c][1, 4]oxaazacyclotricosine-1, 7, 20, 21(23H)-tetrone

Synonyms

Tacrolimus 8-Epimer

References

Sci-Hub, Topical tacrolimus nanocapsules eye drops for therapeutic effect enhancement in both anterior and posterior ocular inflammation models. Journal of Controlled Release, 333, 283–297, 10.1016/j.jconrel.2021.03.035. (2021). Retrieved January 23, 2022, from Sci-hub.ee website: https://sci-hub.ee/https://doi.org/10.1016/j.jconrel.2021.03.035 ?

Status

In-stock