112101-81-2: Tamsulosin EP Impurity B (free base)
Tamsulosin EP Impurity B (free base) (CAS No: 112101-81-2) is a process-related impurity of Tamsulosin. Tamsulosin is a novel type of highly selective 1-adrenergic receptor antagonist having greater specificity for 1 receptor in the human prostate. It is used for the treatment of lower urinary tract symptoms suggestive of Benign prostatic hyperplasia.
Nageswara Rao, R., et al. “Development of a Validated RP-LC/ESI-MS–MS Method for Separation, Identification and Determination of Related Substances of Tamsulosin in Bulk Drugs and Formulations.” Journal of Pharmaceutical and Biomedical Analysis, vol. 46, no. 1, Jan. 2008, pp. 94–103, https://doi.org/10.1016/j.jpba.2007.09.009. ?