152628-02-9Telmisartan EP Impurity A
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| Catalogue No.: | VL142005 |
|---|---|
| CAS No.: | 152628-02-9 |
| Mol. Formula: | C19H20N4 |
| Mol. Weight: | 304.39 g/mol |
Additional information on CAS 152628-02-9
Parent drug
TelmisartanIUPAC Name
4-methyl-6-(1-methyl-1H-benzimidazol-2-yl)-2-propyl-1H-benzimidazolePharmacopeial Synonyms
Telmisartan Related Compound ASynonyms
1,7′-Dimethyl-2′-propyl-2,5′-bibenzimidazole; 2-n-Propyl-4-methyl-6-(1-methylbenzimidazole-2-yl)benzimidazole; N-Des((4-(2-carboxyphenyl)phenyl)methyl) telmisartanSmiles
CCCC1=NC2=C(N1)C=C(C=C2C)C3=NC4=CC=CC=C4N3CInChI
InChI=1S/C19H20N4/c1-4-7-17-20-15-11-13(10-12(2)18(15)22-17)19-21-14-8-5-6-9-16(14)23(19)3/h5-6,8-11H,4,7H2,1-3H3,(H,20,22)Shipping Condition
Ambient TemperatureDescription
Telmisartan EP Impurity A, also designated Telmisartan Related Compound A, CAS 152628-02-9, is the desmethyl, deacidified benzimidazole precursor related to the biphenyl tetrazole antagonist telmisartan. Structurally it is 1,7′-dimethyl-2′-propyl-2,5′-bibenzimidazole, molecular formula C19H20N4, molecular weight 304.39 g/mol. It is typically associated with incomplete benzimidazole alkylation or intermediates retained from synthetic routes rather than oxidative degradation. Because it lacks the acidic pharmacophore of the active drug, its presence is assessed as a route-related organic impurity under pharmacopeial and ICH impurity control expectations. Trace determination generally requires LC-MS/MS, HPLC with diode-array detection, and, where confirmation is needed, NMR and high-resolution MS.Request a Quote
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