Telmisartan EP Impurity A
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Includes: HPLC, MASS/LC-MS, 1H NMR, FT-IR, Potency, Structure Elucidation Report (SER), and additional analytical data depending on the product.

152628-02-9Telmisartan EP Impurity A

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Catalogue No.:VL142005
CAS No.:152628-02-9
Mol. Formula:C19H20N4
Mol. Weight:304.39 g/mol

Additional information on CAS 152628-02-9

Parent drug

Telmisartan

IUPAC Name

4-methyl-6-(1-methyl-1H-benzimidazol-2-yl)-2-propyl-1H-benzimidazole

Pharmacopeial Synonyms

Telmisartan Related Compound A

Synonyms

1,7′-Dimethyl-2′-propyl-2,5′-bibenzimidazole; 2-n-Propyl-4-methyl-6-(1-methylbenzimidazole-2-yl)benzimidazole; N-Des((4-(2-carboxyphenyl)phenyl)methyl) telmisartan

Smiles

CCCC1=NC2=C(N1)C=C(C=C2C)C3=NC4=CC=CC=C4N3C

InChI

InChI=1S/C19H20N4/c1-4-7-17-20-15-11-13(10-12(2)18(15)22-17)19-21-14-8-5-6-9-16(14)23(19)3/h5-6,8-11H,4,7H2,1-3H3,(H,20,22)

Shipping Condition

Ambient Temperature

Description

Telmisartan EP Impurity A, also designated Telmisartan Related Compound A, CAS 152628-02-9, is the desmethyl, deacidified benzimidazole precursor related to the biphenyl tetrazole antagonist telmisartan. Structurally it is 1,7′-dimethyl-2′-propyl-2,5′-bibenzimidazole, molecular formula C19H20N4, molecular weight 304.39 g/mol. It is typically associated with incomplete benzimidazole alkylation or intermediates retained from synthetic routes rather than oxidative degradation. Because it lacks the acidic pharmacophore of the active drug, its presence is assessed as a route-related organic impurity under pharmacopeial and ICH impurity control expectations. Trace determination generally requires LC-MS/MS, HPLC with diode-array detection, and, where confirmation is needed, NMR and high-resolution MS.

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