2028267-73-2: Tofacitinib N-oxide impurity

Status: In-stock

Tofacitinib N oxide impurity (CAS No: 2028267-73-2) Or (3R,4R)-4-Methyl-3-(methyloxido-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-v-oxo-1-piperidinepropanenitrile, Tofacitinib N oxide is an impurity of Tofacitinib, Tofacitinib is a CYP3A4 substrate and a minor CYP2C19 substrate, used in the treatment of rheumatoid arthritis.

Additional information on CAS 2028267-73-2

Catalogue No. VE008142
CAS No. 2028267-73-2
Molecular Formula C16H20N6O2
Molecular Weight 328.38 g/mol
Parent drug Tofacitinib
IUPAC Name (3R, ​4R)​-4-​Methyl-​3-​(methyloxido-​7H-​pyrrolo[2, ​3-​d]​pyrimidin-​4-​ylamino)​-​β-​oxo-1-​piperidinepropanenit​rile
Synonyms N/A
References Sci-Hub, An Improved and Efficient Process for the Preparation of Tofacitinib Citrate, 10.1021/op500274j. (2014). Retrieved January 29, 2022, from Sci-hub.ee website: https://sci-hub.ee/10.1021/op500274j ?
Status In-stock

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2028267-73-2: Tofacitinib N-oxide impurity

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