2028267-73-2: Tofacitinib N-oxide impurity
Tofacitinib N oxide impurity (CAS No: 2028267-73-2) Or (3R,4R)-4-Methyl-3-(methyloxido-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-v-oxo-1-piperidinepropanenitrile, Tofacitinib N oxide is an impurity of Tofacitinib, Tofacitinib is a CYP3A4 substrate and a minor CYP2C19 substrate, used in the treatment of rheumatoid arthritis.
Additional information on CAS 2028267-73-2
Catalogue No.
VE008142
CAS No.
2028267-73-2
Molecular Formula
C16H20N6O2
Molecular Weight
328.38 g/mol
Parent drug
Tofacitinib
IUPAC Name
(3R, 4R)-4-Methyl-3-(methyloxido-7H-pyrrolo[2, 3-d]pyrimidin-4-ylamino)-β-oxo-1-piperidinepropanenitrile
Synonyms
N/A
References
Sci-Hub, An Improved and Efficient Process for the Preparation of Tofacitinib Citrate, 10.1021/op500274j. (2014). Retrieved January 29, 2022, from Sci-hub.ee website: https://sci-hub.ee/10.1021/op500274j ?
Status
In-stock
