Azithromycin EP Impurity E
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内容: HPLC、MASS/LC-MS、1H NMR、FT-IR、含量、構造解析レポート(SER)、および製品に応じた追加分析データ。

612069-27-9Azithromycin EP Impurity E

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カタログ番号:VL186007
CAS番号:612069-27-9
分子式:C36H68N2O12
分子量:720.93 g/mol

に関する追加情報 CAS 612069-27-9

親薬物

Azithromycin

IUPAC名

3-(N,N-didemethyl) Azithromycin

同義語

Amino Azithromycin; (2R, 3S, 4R, 5R, 8R, 10R, 11R, 12S, 13S, 14R)-11-[(3-Amino-3, 4, 6-trideoxy-?-D-xylo-hexopyranosyl)oxy]-13-[(2, 6-dideoxy-3-C-methyl-3-O-methyl-?-L-ribo-hexopyranosyl)oxy]-2-ethyl-3, 4, 10-trihydroxy-3, 5, 6, 8, 10, 12, 14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one; Aminoazithromycin A; Aminoazithromycin Impurity E (EP) ;Azithromycin Impurity E; USP RRT 0.43

Characterization Data (Included)

HPLC, MASS/LC-MS, 1H NMR, FT-IR, Potency, and Structure Elucidation Report (SER).

Additional Characterization Data

QNMR, D2O Exchange, 13C NMR, 13C APT, COSY NMR, NOESY NMR, 15N NMR, HSQC NMR, HMQC NMR, and HMBC NMR. These are available upon request and may be free or subject to additional charges.

説明

Also known as Azithromycin Impurity E, it is an impurity of Azithromycin. Azithromycin is the first member of a group that belongs to macrolide antibiotics called azalides. It is an effective therapeutic agent for the oral treatment of sexually transmitted diseases, upper and lower respiratory tract infections and skin structure infections.

References

Kwiecie?, Anna, et al. Stress Degradation Studies on Azithromycin and Development of a Validated Stability-Indicating TLC-Densitometric Method with HPLC/Electrospray Ionization-MS Analysis of Degradation Products.” Journal of AOAC INTERNATIONAL, vol. 95, no. 5, Sept. 2012, pp. 1418–24, https://doi.org/10.5740/jaoacint.10-196.

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