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内容: HPLC、MASS/LC-MS、1H NMR、FT-IR、含量、構造解析レポート（SER）、および製品に応じた追加分析データ。

118058-74-5Clarithromycin Impurity I

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カタログ番号:	VL740007
CAS番号:	118058-74-5
分子式:	C30H55NO10
分子量:	589.76 g/mol

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に関する追加情報 CAS 118058-74-5

親薬物

Clarithromycin

IUPAC名

3-O-decladinosyl-6-O-methylerythromycin A

薬局方同義語

Clarithromycin EP Impurity I; Decladinosyl Clarithromycin

Other Synonyms

3-O-De(2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)-6-O-methylerythromycin

SMILES

C[C@@](OC)(C[C@H](C([C@@H]1C)=O)C)[C@@H]([C@H]([C@@H]([C@H](C(O[C@H](CC)[C@@](C)(O)[C@@H]1O)=O)C)O)C)O[C@@](O[C@H](C)C[C@@H]2N(C)C)([H])[C@@H]2O

InChI

InChI=1S/C30H55NO10/c1-12-21-30(8,37)25(35)17(4)22(32)15(2)14-29(7,38-11)26(18(5)23(33)19(6)27(36)40-21)41-28-24(34)20(31(9)10)13-16(3)39-28/h15-21,23-26,28,33-35,37H,12-14H2,1-11H3/t15-,16-,17+,18+,19-,20+,21-,23+,24-,25-,26-,28+,29-,30-/m1/s1

説明

Clarithromycin EP Impurity I (CAS No: 118058-74-5) or Des(cladinosyl) Clarithromycin is a degradation product of Clarithromycin. Clarithromycin is a broad-spectrum macrolide antibacterial agent and shows good activity against the major pathogens that cause respiratory tract infections in immunocompetent patients. It is highly active against pathogens causing atypical cases of pneumonia-like Chlamydia pneumoniae, and Legionella spp. and has similar activity to other macrolides against Staphylococcus aureus, Streptococcus pyogenes, Moraxella catarrhalis, and Streptococcus pneumoniae.