(10E)-10,11-didehydro-11-deoxy-6-O-methyl-erythromycin A
同義語
N/A
説明
Clarithromycin EP Impurity N (CAS No: 144604-03-5) or (10E)-10,11-Didehydro-11-deoxy-6-O-methylerythromycin is an impurity of Clarithromycin. Clarithromycin is an acid-stable and orally taken macrolide antimicrobial drug and is structurally similar to erythromycin. It has a broad spectrum of antimicrobial activity and blocks an array of Gram-positive and Gram-negative organisms especially atypical pathogens and some anaerobes.
References
Morgan, Dana, et al. “Impurity Profiling of Clarithromycin Using High-Performance Liquid Chromatography with Ultraviolet Detection.†Journal of Chromatography A, vol. 502, Jan. 1990, pp. 351–58, https://doi.org/10.1016/s0021-9673(01)89599-6. ‌Milne, Richard J., and Karen L. Goa. “Citalopram.†Drugs, vol. 41, no. 3, Mar. 1991, pp. 450–77, https://doi.org/10.2165/00003495-199141030-00008. ‌
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