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포함 사항: HPLC, MASS/LC-MS, 1H NMR, FT-IR, 함량, 구조 규명 보고서(SER), 그리고 제품에 따라 추가 분석 데이터가 제공됩니다.

102728-64-3Acyclovir EP Impurity A

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카탈로그 번호:	VL13001
CAS 번호:	102728-64-3
분자식:	C10H13N5O4
분자량:	267.24 g/mol

견적 요청

RFQ 목록에 추가

에 대한 추가 정보 CAS 102728-64-3

모약물

Acyclovir / Valciclovir

IUPAC명

2-[(2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]ethyl acetate

약전 동의어

Acyclovir Related Compound A; Valciclovir EP Impurity I

Other Synonyms

O-Acetyl Acyclovir; 9-(2-Acetoxyethoxymethyl)guanine; 6H-Purin-6-one, 9-[[2-(acetyloxy)ethoxy]methyl]-2-amino-1,9-dihydro-; 2-[(2-amino-6-oxo-3H-purin-9-yl)methoxy]ethyl acetate; 9-(2-acetoxyethoxy)methylguanine; 2-((2-Amino-6-oxo-1H-purin-9(6H)-yl)methoxy)ethylacetate

SMILES

CC(OCCOCN1C=NC2=C1N=C(N)NC2=O)=O

InChI

InChI=1S/C10H13N5O4/c1-6(16)19-3-2-18-5-15-4-12-7-8(15)13-10(11)14-9(7)17/h4H,2-3,5H2,1H3,(H3,11,13,14,17)

설명

Acyclovir EP Impurity A, also known as Acyclovir Related Compound A; Valciclovir EP Impurity I, in various pharmacopoeias, is a highly characterized standard. It meets strict regulatory requirements set by USP, EMA, JP, and BP, making it a crucial component in Abbreviated New Drug Applications (ANDA), New Drug Applications (NDA), and the commercial production of Acyclovir/ Valciclovir.

References

Huidobro, A. L., et al. â€œLC Methods for Acyclovir and Related Impurities Determination.â€ Journal of Pharmaceutical and Biomedical Analysis, vol. 37, no. 4, Apr. 2005, pp. 687â€“94, https://doi.org/10.1016/j.jpba.2004.11.039. Ilager, Davalasab, et al. â€œSynthesis of Ca-Doped ZnO Nanoparticles and Its Application as Highly Efficient Electrochemical Sensor for the Determination of Anti-Viral Drug, Acyclovir.â€ Journal of Molecular Liquids, vol. 322, Jan. 2021, p. 114552, https://d