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포함 사항: HPLC, MASS/LC-MS, 1H NMR, FT-IR, 함량, 구조 규명 보고서(SER), 그리고 제품에 따라 추가 분석 데이터가 제공됩니다.

36321-43-4Naphazoline EP Impurity A

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카탈로그 번호:	VL1510001
CAS 번호:	36321-43-4
분자식:	C₁₄H₁₆N₂O
분자량:	228.29

견적 요청

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모약물

Naphazoline

IUPAC명

N-(2-Aminoethyl)-2-(naphthalen-1-yl)acetamide

Pharmacopeial Synonyms

Naphthylacetylethylenediamine

Other Synonyms

1-Naphthaleneacetamide, N-(2-aminoethyl)-; N-(2-Aminoethyl)-1-naphthaleneacetamide

SMILES

C1=CC=C2C(=C1)C=CC=C2CC(=O)NCCN

InChl

InChI=1S/C14H16N2O/c15-8-9-16-14(17)10-12-6-3-5-11-4-1-2-7-13(11)12/h1-7H,8-10,15H2,(H,16,17)

설명

Naphazoline EP Impurity A, also referred to in pharmacopoeias as Naphthylacetylethylenediamine, is a meticulously characterized reference standard. It adheres to stringent regulatory guidelines, including those established by USP, EMA, JP, and BP. This product plays a vital role in Abbreviated New Drug Applications (ANDA), New Drug Applications (NDA), and the commercial manufacturing of Naphazoline. Furthermore, it is accompanied by a comprehensive Structure Elucidation Report (SER), ensuring its accuracy and reliability across various analytical applications.

References

“Development and Validation of a Capillary Electrophoretic Method for the Determination of Degradation Product in Naphazoline HCl Bulk Drug Substance.” Journal of Liquid Chromatography & Related Technologies, 2021, www.tandfonline.com/doi/abs/10.1080/10826079808003408.?QUAN, LIN, and HUA HE. “Treatment with Olopatadine and Naphazoline Hydrochloride Reduces Allergic Conjunctivitis in Mice through Alterations in Inflammation, NGF and VEGF.” Molecular Medicine Reports, vol. 13, no. 4, Feb. 2016, pp.