Naphazoline EP Impurity D (CAS No: 22126-67-6) is an impurity present in Naphazoline which is an alpha-adrenergic and sympathomimetic agent used in topical nasal or ophthalmic pharmaceutical formulations. It is a vasoconstrictor with a rapid and prolonged action in overcoming swelling and congestion when applied to mucous membranes.
References
“Development and Validation of a Capillary Electrophoretic Method for the Determination of Degradation Product in Naphazoline HCl Bulk Drug Substance.†Journal of Liquid Chromatography & Related Technologies, 2021, www.tandfonline.com/doi/abs/10.1080/10826079808003408.Wall, G. Michael. “Naphazoline Hydrochloride.†Analytical Profiles of Drug Substances and Excipients, 1992, pp. 307–44, https://doi.org/10.1016/s0099-5428(08)60396-2.
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