Pantoprazole EP Impurity C는 Pantoprazole BP Impurity C, Pantoprazole Related Compound C, Pantoprazole Thiol Impurity로도 불리며, 5-(difluoromethoxy)-2-mercapto-1H-benzimidazole, CAS 97963-62-7에 해당한다. 분자식 C8H6F2N2OS, 분자량 216.21 g/mol의 이 물질은 pantoprazole 합성 경로에서 유래하는 공정 관련 불순물 및 합성 중간체이다. 일반적으로 불완전한 고리화 또는 전구체 잔류를 시사하며, 산화 분해산으로 보기 어렵다. 벤즈이미다졸-티올 작용기의 극성 때문에 미량 수준 분석이 필요하며, 동정과 정량에는 LC-MS/MS, 다이오드어레이 검출 HPLC, 필요 시 유도체화 후 GC-MS가 요구된다.
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