Almotriptan Impurities

Almotriptan is used for the relief of migraine headache symptoms (severe, throbbing headaches accompanied by nausea and sensitivity to sound and light).

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Parent Drug Name Name of Impurity Catalogue No.
Almotriptan Almotriptan EP Impurity B Malate VE0012096View
Almotriptan Almotriptan EP Impurity F Malate VE0012097View
Almotriptan Almotriptan Hydrazine Precursor HCl VE0012095View CAS 334981-11-2
Almotriptan Almotriptan Impurity 1 VE0012098View CAS 334981-13-4
Almotriptan Almotriptan Impurity 4 VE0012099View CAS 334981-31-6
Almotriptan Almotriptan Impurity 6 (2HCl) VE0012100View
Almotriptan Almotriptan Impurity 7 VE0012101View
Almotriptan Almotriptan Impurity 8 VE0012102View CAS 1042449-29-5
Almotriptan Almotriptan Impurity 9 VE0012103View
Almotriptan Almotriptan N-Dimer Impurity VE006948View
Almotriptan Almotriptan N-Isopropyl Impurity VE006947View
Almotriptan Almotriptan N-Oxide VE0012135View
Almotriptan Almotriptan Related Compound A VL264001View CAS 1018676-02-2
Almotriptan Almotriptan Related Compound B VL264002View CAS 181178-24-5
Almotriptan Almotriptan Related Compound C VL264003View CAS 334981-12-3
Almotriptan Almotriptan Related Compound D VL264004View
Almotriptan Almotriptan-D6 Malate DVE0026View
Almotriptan Gamma-Aminobutyric Acid Almotriptan VL264018View CAS 603137-41-3
Almotriptan Spiro Almotriptan VL264011View
Almotriptan Spiroalmotriptan VE0011420View CAS 1309457-18-8

Abacavir Related Compound

Almotriptan belongs to the class of drugs known as selective serotonin receptor agonists.



What is the mechanism of action of almotriptan?

Almotriptan is a selective serotonin agonist on the cranial artery 5-HT1B and 5-HT1D receptors. The stimulation of the 5HT receptors is linked to a reduction in neurogenic inflammation, which experts believe is important in the migraine treatment process.

What class of drug is almotriptan?

Almotriptan is a triptan medication used to treat migraine headaches. Almotriptan belongs to a class of drugs known as selective serotonin receptor agonists.

What is the therapeutic use of almotriptan?

It works by constricting blood arteries in the brain, preventing pain signals from reaching the brain, and preventing the production of certain natural compounds that produce pain, nausea, and other migraine symptoms.


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1018676-02-2: Almotriptan Related Compound A

1018676-02-2: Almotriptan Related Compound A
Catalogue No.




Molecular Formula


Molecular Weight


Parent drug



{3-[2-(dimethylamino)-ethyl]-5-[(pyrrolidin-1-yl-sulfonyl)methyl]-1H-indol-1-yl}- methanol


Almotriptan Related Compound A / Almotriptan Hydroxymethyl Impurity


Kumar, A. Phani, et al. “A Validated Reversed Phase HPLC Method for the Determination of Process-Related Impurities in Almotriptan Malate API.” Journal of Pharmaceutical and Biomedical Analysis, vol. 46, no. 4, Mar. 2008, pp. 792–98, ?Orlandini, S., et al. “An Integrated Quality by Design and Mixture-Process Variable Approach in the Development of a Capillary Electrophoresis Method for the Analysis of Almotriptan and Its Impurities.” Journal of Chroma




Almotriptan Related Compound A

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