| Parent Drug Name | Name of Impurity | Catalogue No. | |
|---|---|---|---|
| Rivaroxaban | Dioxazolidine Impurity | VE008973 | View |
| Rivaroxaban | N-(2-hydroxyethyl)-N-phenylnitrous amide | VE009423 | View CAS 25413-76-7 |
| Rivaroxaban | N-(3-(1, 3-dioxoisoindolin-2-yl)-2-hydroxypropyl)-N-(4-(3-oxomorpholino)phenyl)nitrous amide | VE009424 | View |
| Rivaroxaban | N-(S)-Glycidylphthalimide | VE006990 | View CAS 161596-47-0 |
| Rivaroxaban | Rivaroxaban Aminomethyl Impurity | VE006551 | View CAS 898543-06-1 |
| Rivaroxaban | Rivaroxaban Aminomethyl Impurity (Free Base) | VE006988 | View CAS 446292-10-0 |
| Rivaroxaban | Rivaroxaban Descarbonyl Impurity | VE006370 | View CAS 721401-53-2 |
| Rivaroxaban | Rivaroxaban Diamide | VE008976 | View CAS 1838133-00-8 |
| Rivaroxaban | Rivaroxaban Diol | VE008974 | View CAS 1160170-00-2 |
| Rivaroxaban | Rivaroxaban EP Impurity B | VE006402 | View CAS 1429334-00-8 |
| Rivaroxaban | Rivaroxaban EP Impurity D | VL2140007 | View CAS 1365267-35-1 |
| Rivaroxaban | Rivaroxaban EP Impurity E | VL2140008 | View CAS 1415566-28-7 |
| Rivaroxaban | Rivaroxaban EP Impurity F | VE007629 | View CAS 24065-33-6 |
| Rivaroxaban | Rivaroxaban EP Impurity G | VE006403 | View CAS 446292-08-6 |
| Rivaroxaban | Rivaroxaban EP Impurity H | VL2140010 | View CAS 1770812-37-7 |
| Rivaroxaban | Rivaroxaban EP Impurity I | VE006404 | View CAS 1151893-81-0 |
| Rivaroxaban | Rivaroxaban EP Impurity J | VE006405 | View CAS 1632463-24-1 |
| Rivaroxaban | Rivaroxaban Impurity 107 | VE0010467 | View CAS 1257527-98-2 |
| Rivaroxaban | Rivaroxaban Impurity 34 | VE0010274 | View CAS 1643354-27-1 |
| Rivaroxaban | Rivaroxaban Impurity 48 | VE009777 | View CAS 1325210-62-5 |
| Rivaroxaban | Rivaroxaban Impurity 6 | VE006989 | View CAS 438056-69-0 |
| Rivaroxaban | Rivaroxaban Impurity I | VL2140001 | View CAS 530-62-1 |
| Rivaroxaban | Rivaroxaban Impurity II | VL2140002 | View CAS 85-41-6 |
| Rivaroxaban | Rivaroxaban Impurity III | VL2140003 | View CAS 1074-82-4 |
| Rivaroxaban | Rivaroxaban Inhouse Impurity A | VE008521 | View CAS 1265617-06-8 |
| Rivaroxaban | Rivaroxaban N-Methylphthalimide Impurity | VE009341 | View CAS 550-44-7 |
| Rivaroxaban | Rivaroxaban Nitrosamine Impurity I | VE0010627 | View |
| Rivaroxaban | Rivaroxaban Nitrosamine Impurity II | VE0010628 | View |
| Rivaroxaban | Rivaroxaban Open-Ring Acid | VE008080 | View CAS 931204-39-6 |
| Rivaroxaban | Rivaroxaban Open-Ring Acid (HCl) | VE009902 | View CAS 931117-61-2 |
| Rivaroxaban | Rivaroxaban Open-Ring N-Methyl Impurity | VE006997 | View CAS 1807455-76-0 |
| Rivaroxaban | Rivaroxaban Phthalamide Dimer | VE007984 | View CAS 1365267-36-2 |
| Rivaroxaban | Rivaroxaban R-isomer impurity | VL2140005 | View CAS 865479-71-6 |
| Varenicline | 1,5,6,7,8,9-Hexahydro-5,9-methanoimidazo[4,5-h][3]benzazepine hydrochloride | VE0010394 | View CAS 230615-10-8 |
| Rivaroxaban | 2-(2-((4-((3-(5-Chlorothiophene-2-carboxamido)-2-hydroxypropyl)amino)phenyl)amino)ethoxy)acetic Acid Hydrochloride | VE009115 | View CAS 1620129-74-9 |
| Rivaroxaban | 3-Chloro Rivaroxaban | VE008978 | View CAS 1855920-54-5 |
| Rivaroxaban | 3-Morpholinone | VE0010506 | View CAS 109-11-5 |
| Rivaroxaban | 4, 5-Dichlorothiophene-2-carboxylic Acid | VE006646 | View CAS 31166-29-7 |
| Rivaroxaban | 4-[((2R)-Hydroxy-3-phthalimido)propylamine]phenyl-3-morpholinone | VE009365 | View CAS 446292-07-5 |
| Rivaroxaban | 4-[4-[(3-Aminopropyl)amino]phenyl]-3-morpholinone | VE008977 | View CAS 1816946-19-6 |
| Rivaroxaban | 5-Chloro-N-(2-hydroxy-3-((4-(3-oxomorpholino)phenyl)amino)propyl)thiophene-2-carboxamide | VE009903 | View CAS 482305-98-6 |
| Rivaroxaban | (S)-4-(4-(5-(aminomethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one hydrobromide | VE009938 | View |
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Rivaroxaban Related Compound
Rivaroxaban is used to treat individuals with deep vein thrombosis (DVT; a blood clot in the leg) and pulmonary embolism (PE; a blood clot in the lung).
References
- “XARELTO® (Rivaroxaban) | Healthcare Professional Website.” XARELTO® (Rivaroxaban), 12 Apr. 2021, www.xareltohcp.com/dosing-all-indications#:~:text=XARELTO%C2%AE%20(rivaroxaban)%20is%20indicated,of%20pulmonary%20embolism%20(PE). Accessed 16 Mar. 2023.
- “Rivaroxaban: MedlinePlus Drug Information.” Medlineplus.gov, 2022, medlineplus.gov/druginfo/meds/a611049.html#:~:text=Rivaroxaban%20is%20in%20a%20class,helps%20blood%20clots%20to%20form. Accessed 16 Mar. 2023.
- Ichikawa, Hiroaki, et al. “Rivaroxaban, a Direct Factor Xa Inhibitor, Ameliorates Hypertensive Renal Damage through Inhibition of the Inflammatory Response Mediated by Protease‐Activated Receptor Pathway.” Journal of the American Heart Association, vol. 8, no. 8, Apr. 2019, https://doi.org/10.1161/jaha.119.012195. Accessed 16 Mar. 2023.
FAQ
What are the indications for rivaroxaban use?
In adult patients with nonvalvular atrial fibrillation, rivaroxaban is used to minimize the risk of stroke and systemic embolism (AF). Rivaroxaban is used for the treatment of deep vein thrombosis (DVT). also used to treat pulmonary embolism (PE).
Which drug class does rivaroxaban belong to?
Rivaroxaban belongs to a class of drugs known as factor Xa inhibitors. It works by inhibiting the function of a natural chemical that aids in the formation of blood clots.
Is rivaroxaban used for hypertension?
Rivaroxaban, a Direct Factor Xa Inhibitor, Reduces Hypertensive Renal damage by Blocking the Inflammatory Response Mediated by the Protease Activated Receptor Pathway.
