Indomethacin Impurity 3 (sal de sódio) | CAS 5446-07-1 | é uma impureza relacionada estruturalmente ao indometacina que pode surgir durante a síntese ou por degradação no armazenamento. Apresenta propriedades físico-químicas distintas do composto parental | incluindo maior solubilidade em meio aquoso devido à forma salina | o que altera seu comportamento em ensaios analíticos. A identificação e quantificação são realizadas por técnicas como HPLC | LC-MS e RMN | permitindo caracterização de massa e perfis de impurezas correlacionadas. A presença desta impureza é monitorada em perfis de estabilidade e controle de qualidade para avaliar potenciais impactos na pureza e conformidade regulatória.
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