A impureza 2 | 3 | 5-Tri-O-acetil α-Adenosina (CAS 953089-09-3) surge tipicamente como subproduto da acetilação de nucleósidos | resultando de acetilação parcial | isomerização anomérica ou reações secundárias durante síntese e armazenamento. No controle de qualidade é identificada e quantificada por HPLC com detecção UV | confirmada por RMN e espectrometria de massa | sendo parte essencial do perfil de impurezas. Esta espécie pode afetar o teor | a estabilidade e a reprodutibilidade de lotes | exigindo procedimentos de purificação como cromatografia em fase normal ou reversa e recristalização | além de limites e métodos validados em conformidade com ICH para garantir qualidade.
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![8-Amino[1''-(N''-dansyl)-4''-aminobutyl]-5'-(1-aziridinyl)-5'-deoxy adenosine](https://veeprho.com/wp-content/uploads/2022/07/8-Amino5B1-N-dansyl-4-aminobutyl5D-5-1-aziridinyl-5-deoxy-adenosine.png "8-Amino[1''-(N''-dansyl)-4''-aminobutyl]-5'-(1-aziridinyl)-5'-deoxy adenosine")
