(R)-1-(3-Aminofenil)-2-(metilamino)etanol (CAS 50741-74-7) é uma impureza quiral frequentemente identificada em matérias-primas e intermediários farmacêuticos; apresenta grupo amino aromático e álcool secundário que conferem polaridade e reatividade. Sua presença exige perfilagem de impurezas por HPLC e HPLC quiral | LC-MS e RMN para quantificação e identificação estrutural. Pode originar-se por reações secundárias na síntese | hidrólise ou epimerização | e afetar pureza e estabilidade do produto final. Controlos analíticos | limites especificados conforme ICH | estratégias de purificação cromatográfica e estudos de degradação forense são recomendados para mitigar riscos de segurança e qualidade.
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