Informações adicionais sobre o Bromfenac Impurity 4 (Sodium Salt)
Fármaco de origem
Bromfenac
Nome IUPAC
2-amino-3-(4-bromobenzoyl)benzoic acid, sodium salt (1:1)
Sinônimos
N/A
Descrição
O Bromfenac Impurity 4 (Sodium Salt) é uma impureza relacionada ao processo de síntese do bromfenac e ao seu armazenamento | caracterizada por um perfil analítico claro obtido por cromatografia líquida de alta resolução | espectrometria de massa e RMN que asseguram identificação e quantificação robustas. A forma salina influencia solubilidade e comportamento em fase móvel | exigindo otimização de métodos e validação específica. Estudos forçados e de estabilidade definem seu padrão de degradação e suportam a definição de especificações | limites de controle e estratégias de mitigação aplicáveis ao desenvolvimento e ao controle de qualidade para atender requisitos regulatórios.
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![(3,3'-dibromo-1H,1'H-[5,5'-biindole]-7,7'-diyl)bis((4-bromophenyl)methanone)](https://veeprho.com/wp-content/uploads/2023/05/3-3-dibromo-1H-1-H-5-5-biindole-7-7-diyl-bis-4-bromophenyl-methanone.png "(3,3'-dibromo-1H,1'H-[5,5'-biindole]-7,7'-diyl)bis((4-bromophenyl)methanone)")
![1H,1'H-[5,5'-biindole]-7,7'-diylbis((4-bromophenyl)methanone)](https://veeprho.com/wp-content/uploads/2023/05/1H-1-H-5-5-biindole-7-7-diylbis-4-bromophenyl-methanone.png "1H,1'H-[5,5'-biindole]-7,7'-diylbis((4-bromophenyl)methanone)")
