Citalopram EP Impurity E (Oxalate) | CAS 1329612-81-8 | também conhecida como Citalopran Related Compound G (Oxalate) ou 5-chlorodescyano citalopram oxalate | é uma impureza identificada na cadeia de síntese do citalopram. Trata-se do sal de oxalato de um análogo contendo núcleo benzofurano 5-clorado e grupo N | N-dimetilpropan-1-amina com anel 4-fluorofenil. Características analíticas incluem maior polaridade relativa | padrão de retenção em HPLC reverso | perfil de massa por LC-MS e sinais diagnósticos em RMN. A sua quantificação e controle por métodos validados é essencial para conformidade com Ph. Eur. e garantia de pureza do material ativo | bem como para investigação de vias de degradação.
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