Clarithromycin Impurity G; 6-O-Methylerythromycin (9E)-9-(O-Methyloxime); Clarithromycin Impurity G; Clarithromycin EP Impurity G
Descrição
A Clarithromycin Impurity G (CAS 127182-44-9) | também conhecida como 6-O-Methylerythromycin (9E)-9-(O-Methyloxime) ou Clarithromycin EP Impurity G | é uma impureza relacionada ao composto ativo que exige controle analítico rigoroso durante desenvolvimento e liberação. Caracteriza-se por propriedades físico-químicas que a distinguem do princípio ativo e é quantificada por técnicas cromatográficas validadas como HPLC com detecção UV e confirmada por LC-MS e RMN para identificação estrutural. Sua presença influencia o perfil de pureza | avaliação de estabilidade e conformidade com monografias farmacêuticas | por isso recomenda-se uso de padrão de referência | limites de especificação apropriados e armazenamento controlado para garantir integridade das análises.
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