A Impureza EP B de Diclofenaco, também designada Diclofenac Related Compound B ou análogo benzaldeído de diclofenaco, é o precursor aldeídico o-(2,6-dicloroanilino)benzaldeído, CAS 22121-58-0, com fórmula C13H9Cl2NO e massa molecular de 266,12 g/mol. Este aminobenzaldeído aromático enquadra-se como intermediário de síntese e impureza associada ao processo na fabricação de diclofenaco, podendo resultar de conversão incompleta ou oxidação da cadeia lateral antes da formação do motivo ácido fenilacético. A determinação em nível de traço normalmente exige LC-MS/MS, LC-UV com separação específica de impurezas e, quando necessário, GC-MS após derivatização.
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