59-48-3Diclofenac EP Impurity E

Diclofenac EP Impurity E, also referred to in pharmacopoeias as Oxindole; Diclofenac Related Compound E, is a meticulously characterized reference standard. It adheres to stringent regulatory guidelines, including those established by USP, EMA, JP, and BP. This product plays a vital role in Abbreviated New Drug Applications (ANDA), New Drug Applications (NDA), and the commercial manufacturing of Diclofenac. Furthermore, it is accompanied by a comprehensive Structure Elucidation Report (SER), ensuring its accuracy and reliability across various analytical applications. Also known as Diclofenac Related Compound E, Diclofenac Oxindole Impurity, Indolin-2-one, 1,3-Dihydro-2H-indol-2-one, 2-Indolinone, Oxindole, 2-Oxindole, 2-Oxoindoline or Diclofenac Oxindole Impurity is a metabolite of Diclofenac which is a non-steroidal anti-inflammatory agent (NSAID) to be accepted as a phenylacetic acid derivative and is known to compete with arachidonic acid for attaching to cyclo-oxygenase which results in the diminished formation of prostaglandins.