5-(4′-Methylbiphenyl-2-yl)-1H-tetrazole Pottassium Salt
Sinônimos farmacopeicos
N/A
Outros sinônimos
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SMILES
CC1=CC=C(C2=CC=CC=C2C3=N[N-]N=N3)C=C1.[K+]
Descrição
Losartan EP Impurity E (sal potássio) | CAS 860644-27-5 | é uma impureza relacionada ao processo de síntese e à degradação do princípio ativo que requer monitoramento rigoroso. Caracteriza-se por propriedades físico-químicas específicas que demandam técnicas analíticas sensíveis como HPLC | LC-MS e RMN para identificação | quantificação e elucidação estrutural. A presença desta impureza pode influenciar o perfil de pureza e a estabilidade do lote | exigindo limites de especificação e critérios de aceitação bem definidos. Estratégias de controle incluem otimização do processo | purificação dirigida | validação de métodos analíticos e avaliação contínua do perfil de impurezas para garantir conformidade regulatória.
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