1,8-Diazabicyclo[5.4.0]undec-7-ene
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0 % Toleranz bei der Produktqualität

Lagerstandorte

  • New Jersey, USA
  • Czech Republic, EU
  • Mumbai, India

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Dokumentation

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Enthält: HPLC, MASS/LC-MS, 1H-NMR, FT-IR, Gehalt, Structure Elucidation Report (SER) sowie zusätzliche analytische Daten je nach Produkt.

6674-22-21,8-Diazabicyclo[5.4.0]undec-7-ene

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Katalog-Nr.::VE008082
CAS-Nr.::6674-22-2
Summenformel::C9H16N2
Molare Masse::152.24 g/mol

Zusätzliche Informationen zu CAS 6674-22-2

Parent drug

Tofacitinib

IUPAC-Name

2, 3, 4, 6, 7, 8, 9, 10-octahydropyrimido[1, 2-a]azepine

Pharmakopöe-Synonyme

N/A

Other Synonyms

1,8-Diaza-7-bicyclo[5.4.0]undecene; 1,8-Diazabicyclo[5.4.0]undecene-7

SMILES

C2CCC1=NCCCN1CC2

InChI

InChI=1S/C9H16N2/c1-2-5-9-10-6-4-8-11(9)7-3-1/h1-8H2

Shipping Condition

Ambient Temperature

Characterization Data (Included)

HPLC, MASS/LC-MS, 1H NMR, FT-IR, Potency, and Structure Elucidation Report (SER).

Additional Characterization Data

QNMR, D2O Exchange, 13C NMR, 13C APT, COSY NMR, NOESY NMR, 15N NMR, HSQC NMR, HMQC NMR, and HMBC NMR. These are available upon request and may be free or subject to additional charges.

Beschreibung

1,8-Diazabicyclo[5.4.0]undec-7-ene (CAS No: 6674-22-2) shows excellent catalytic activity in the Baylis–Hillman reaction. DBU is studied as a promoter for the aza-Michael reaction mainly used for constructing b-aminocarbonyl compounds. B-aminocarbonyl compounds are utilized as building blocks for various nitrogen-containing biologically essential compounds.

References

Yeom, Chang-Eun, et al. “1, 8-Diazabicyclo[5.4.0]Undec-7-Ene (DBU)-Promoted Efficient and Versatile Aza-Michael Addition.” Tetrahedron, vol. 63, no. 4, Jan. 2007, pp. 904–9, https://doi.org/10.1016/j.tet.2006.11.037. ?

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