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15307-86-5Aceclofenac EP Impurity A

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Katalog-Nr.::	VL284007
CAS-Nr.::	15307-86-5
Summenformel::	C14H11Cl2NO2
Molare Masse::	296.15 g/mol

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Zusätzliche Informationen zu CAS 15307-86-5

Parent drug

Aceclofenac

Characterization Data (Included)

HPLC, MASS/LC-MS, 1H NMR, FT-IR, Potency, and Structure Elucidation Report (SER).

Additional Characterization Data

QNMR, D2O Exchange, 13C NMR, 13C APT, COSY NMR, NOESY NMR, 15N NMR, HSQC NMR, HMQC NMR, and HMBC NMR. These are available upon request and may be free or subject to additional charges.

IUPAC-Name

2-(2-((2,6-dichlorophenyl)amino)phenyl)acetic acid

Pharmacopeial Synonyms

Diclofenac

Synonyme

Benzeneacetic acid, 2-[(2,6-dichlorophenyl)amino]-; Diclofenac acid; [ 2-(2,6-Dichloroanilino)phenyl]acetic acid

SMILES

C1=CC=C(C(=C1)CC(=O)O)NC2=C(C=CC=C2Cl)Cl

InChI

InChI=1S/C14H11Cl2NO2/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19/h1-7,17H,8H2,(H,18,19)

Shipping Condition

Ambient Temperature

Beschreibung

Aceclofenac EP Impurity A, also referred to in pharmacopoeias as Diclofenac, is a meticulously characterized reference standard. It adheres to stringent regulatory guidelines, including those established by USP, EMA, JP, and BP. This product plays a vital role in Abbreviated New Drug Applications (ANDA), New Drug Applications (NDA), and the commercial manufacturing of Aceclofenac. Furthermore, it is accompanied by a comprehensive Structure Elucidation Report (SER), ensuring its accuracy and reliability across various analytical applications. Also known as Diclofenac Sodium, Dichlofenac, Diclofenac Acid, it is a non-steroidal anti-inflammatory drug (NSAID) supported for use in painful and inflammatory rheumatic and some non-rheumatic conditions. It suppresses acute and chronic inflammation, pain, and hyperthermia in various animal models.

References

Todd, Peter A., and Eugene M. Sorkin. “Diclofenac Sodium.” Drugs, vol. 35, no. 3, Mar. 1988, pp. 244–85, https://doi.org/10.2165/00003495-198835030-00004. ?