Bupropion Related Compound C, CAS 152943-33-4, ist eine chlorierte aromatische Ketonverunreinigung, die mit dem Syntheseweg von Bupropion verbunden ist und aus Überreaktionen eines Zwischenprodukts oder unvollständiger Seitenkettenausarbeitung entstehen kann. Mit der Summenformel C9H9ClO2 und einer Molekülmasse von 184,62 g/mol handelt es sich um eine strukturell definierte prozessbedingte Verunreinigung und nicht um ein Abbauprodukt. Das aromatische Chloroketon-Motiv erfordert bei der Charakterisierung hohe Selektivität, typischerweise mittels LC-MS/MS zur Spurenquantifizierung und Bestätigung, ergänzt durch HPLC mit Diodenarraydetektion und, sofern die Flüchtigkeit es zulässt, GC-MS. Regulatorisch stehen Spezifikation, Herkunftskontrolle und konsistentes Verunreinigungsprofil im Fokus.
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