Impureza (3-chloro-4,5-dihydroxyphenyl)(1,1-dioxidobenzo[d]thiazol-3(2H)-yl)methanone presenta un perfil polar elevado debido a los grupos dihidroxilo y la unidad sulfona en el anillo benzotiazólico, lo que favorece retenciones cortas en HPLC reverso y fuerte ionización en ESI-MS positiva y negativa. Su masa y fragmentación diagnosticable permiten identificación por LC-MS/HRMS, mientras que IR y RMN 1H/13C confirman conectividad y sustitución clorada. Como impureza puede afectar la estabilidad oxidativa y la solubilidad del lote, por ello se recomiendan límites de aceptación basados en riesgo, controles de proceso, purificación por recristalización y métodos analíticos validados para su cuantificación.
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![(3-chloro-4,5-dihydroxyphenyl)(1,1-dioxidobenzo[d]thiazol-3(2H)-yl)methanone](https://veeprho.com/wp-content/uploads/2026/03/3-chloro-45-dihydroxyphenyl11-dioxidobenzodthiazol-32H-ylmethanone-NA-VE0027997-sqr.png "(3-chloro-4,5-dihydroxyphenyl)(1,1-dioxidobenzo[d]thiazol-3(2H)-yl)methanone")
