Atorvastatin Related Compound A, también denominado desfluoroatorvastatina y Atorvastatin EP Impurity A, es la sal cálcica de un análogo de atorvastatina carente de flúor, CAS 433289-83-9. Presenta fórmula C66H70CaN4O10 como sal y C33H36N2O5 como base libre, con un peso molecular de 1119.38 g/mol para la sal cálcica y 540.65 g/mol para la especie neutra. Esta impureza de proceso o de síntesis se origina por la sustitución del motivo farmacóforo p-fluorofenilo por un fenilo no sustituido. Su control suele requerir LC-MS/MS con separación cromatográfica frente a atorvastatina y sustancias relacionadas, y la confirmación estructural puede apoyarse en HRMS y RMN.
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