El ácido ciclopropanocarboxílico, CAS 1759-53-1, es un ácido carboxílico alicíclico de baja masa molecular, con fórmula C4H6O2 y peso molecular de 86,09 g/mol. Como impureza estructural, puede originarse a partir de intermedios ciclopropílicos, hidrólisis o carboxilación incompleta durante la síntesis de sustancias activas e intermedios relacionados. La tensión del anillo de tres miembros y la función ácida condicionan su volatilidad, comportamiento cromatográfico y respuesta a la derivatización. Dado que suele presentarse a nivel traza, su determinación exige con frecuencia GC-MS o LC-MS/MS, a menudo con monitorización selectiva de iones. No se clasifica como impureza genotóxica típica.
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