Epinephrine Impurity 17 es una impureza identificada en procesos de síntesis y degradación de epinefrina que puede formarse por oxidación y reacciones de reordenamiento bajo condiciones alcalinas o exposición a oxígeno. La caracterización exige técnicas analíticas avanzadas como HPLC-UV | LC-MS y 1H/13C NMR para confirmar estructura y cuantificar niveles en el perfil de impurezas. Su presencia puede comprometer la potencia y la estabilidad del principio activo | por eso se controla según guías ICH mediante límites específicos y desarrollo de métodos validados. Estrategias de mitigación incluyen antioxidantes | control de pH | envasado inerte y purificación cromatográfica preparativa.
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