Losartan EP Impurity K (Losartan Related Compound C | Losartan Aldehyde) | CAS 114798-36-6 | es una impureza aldehídica derivada de procesos de oxidación o degradación de intermediarios en la síntesis de losartan; su detección y cuantificación son críticas para garantizar la calidad del principio activo. Técnicamente | requiere métodos analíticos validados como HPLC con detección UV y confirmación por LC-MS y RMN para establecer identidad y pureza. El control de esta impureza incluye optimización de condiciones de síntesis | etapas de purificación y estabilidad bajo almacenamiento. Su monitorización según límites de impurezas establecidos por guías regulatorias es esencial para la liberación y seguridad del lote.
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